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Table 4 Distributions of TT, CT and CC genotypes and T and C alleles in C3435T polymorphism of MDR1 gene in the group of children with drug-resistant epilepsy and in the group of drug-responsive epilepsy

From: Association between C3435T polymorphism of MDR1 gene and the incidence of drug-resistant epilepsy in the population of Polish children

  Children with drug-resistant epilepsy (n = 106) Children with drug-responsive epilepsy (n = 67) OR (95 % CIa)b p c
Number (%) Number (%)
CC 35 33 16 24 1.00 Ref.d  
CT 39 37 18 27 0.99 (0.44–2.23) 0.862
TT 32 30 33 49 0.44 (0.21–0.95) 0.036
C 109 51 50 37 1.00 Ref.  
T 103 49 84 63 0.56 (0.36–0.87) 0.014
  1. aAnalysis of odds ratio (OR odds ratio, PU Confidence Interval 95 %)
  2. bAdjusted for age and use of variety of drugs
  3. cFor the test of χ2 conformity with the distribution predicted by the Hardy–Weinberg law
  4. dReference group—wild type of allele