Association between C3435T polymorphism of MDR1 gene and the incidence of drug-resistant epilepsy in the population of Polish children

Table 5 Distributions of TT, CT and CC genotypes and T and C alleles in C3435T polymorphism of MDR1 gene in the group of children with drug-responsive epilepsy and in the group of healthy children

	Children with drug-responsive epilepsy (n = 67)		Healthy children (n = 98)		OR (95 % CI^a)^b	p ^c
	Number	(%)	Number	(%)	OR (95 % CI^a)^b	p ^c
CC	16	24	16	16	1.00 Ref.^d
CT	18	27	37	38	0.48 (0.19–1.18)	0.172
TT	33	49	45	46	0.73 (0.32–1.67)	0.596
C	50	37	69	35	1.00 Ref.
T	84	63	127	65	0.92 (0.58–1.44)	0.777

^aAnalysis of odds ratio (OR odds ratio, PU Confidence Interval 95 %)
^bAdjusted for age and use of variety of drugs
^cFor the test of χ² conformity with the distribution predicted by the Hardy–Weinberg law
^dReference group—wild type of allele

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