Skip to main content

Table 2 Associations between the plasma metabolites and ADHD-like behavioural scores (total ADHD, inattention, impulsivity)

From: A non-targeted metabolite profiling pilot study suggests that tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs

Putative annotation

Total ADHD

Inattention

Impulsivity

rs

praw

pFDR

rs

praw

pFDR

rs

praw

pFDR

Putative carnitine

0.505

0.017

0.990

0.450

0.036

0.990

0.509

0.016

0.797

1-methylnicotinamide

0.647

0.001

0.618

0.668

6.86E-04

0.455

0.571

0.005

0.461

Kynurenic acid (KYNA)

0.511

0.015

0.426

0.505

0.017

0.392

0.498

0.018

0.447

Phelynalanine

0.403

ns

ns

0.337

ns

ns

0.425

0.049

0.989

Indoleacetic acid

−0.404

ns

ns

−0.474

0.030

0.433

−0.349

ns

ns

3-Indolepropionic acid (IPA)

−0.565

0.006

0.381

−0.618

0.002

0.241

−0.452

0.035

0.560

Unknown metabolite m/z 221.150

0.443

0.039

0.990

0.520

0.013

0.873

0.287

ns

ns

sn-1 LysoPC(14:0)

−0.390

ns

ns

−0.424

0.049

0.510

−0.360

ns

ns

sn-1 LysoPC(18:3)

−0.769

2.93E-05

0.016

−0.740

8.26E-05

0.030

−0.765

3.32E-05

0.036

sn-1 LysoPE(20:5)

−0.544

0.009

0.409

−0.615

0.002

0.241

−0.447

0.037

0.560

sn-1 LysoPC(15:0)

−0.623

0.002

0.330

−0.602

0.003

0.241

−0.659

8.46E-04

0.320

sn-1 LysoPE(18:2)

−0.630

0.002

0.093

−0.697

3.1E-04

0.044

−0.549

0.008

0.230

sn-1 LysoPE(18:1)

−0.382

ns

ns

−0.530

0.011

0.117

−0.218

ns

ns

sn-1 LysoPC(20:3)

−0.508

0.016

0.426

−0.489

0.021

0.409

−0.516

0.014

0.437

sn-1 LysoPC(17:0)

−0.451

0.035

0.491

−0.438

0.041

0.473

−0.441

0.038

0.566

sn-1 LysoPE(18:0)

−0.562

0.006

0.146

−0.574

0.005

0.102

−0.539

0.01

0.232

Arachidonic acid (C20:4)

0.508

0.016

0.163

0.579

0.005

0.102

0.355

ns

ns

Unknown metabolite, putative GlcCer(d18:1/12:0) or GlcCer(d14:1/16:0)

0.504

0.017

0.163

0.524

0.012

0.117

0.447

0.037

0.302

C18:1

0.509

0.016

0.426

0.532

0.011

0.342

0.477

0.025

0.492

Unknown metabolite, putative Cer(d18:1/24:1)

0.509

0.016

0.163

0.536

0.010

0.117

0.461

0.031

0.283

Bilirubin

0.513

0.015

0.426

0.580

0.005

0.271

0.452

0.035

0.560

PC(20:5/18:3)

−0.555

0.009

0.150

−0.621

0.003

0.087

−0.415

ns

ns

Unknown PC m/z 796.516

−0.413

ns

ns

−0.465

0.029

0.173

−0.299

ns

ns

PC(20:4/14:0)

−0.558

0.007

0.148

−0.557

0.007

0.110

−0.485

0.022

0.281

PC(18:3/18:2)

−0.804

1.91E-05

0.016

−0.798

2.53E-05

0.019

−0.731

2.52E-04

0.137

PC(18:2/16:1)

−0.518

0.013

0.163

−0.500

0.018

0.137

−0.486

0.022

0.281

PC(15:0/18:2)

−0.578

0.005

0.381

−0.568

0.006

0.305

−0.525

0.012

0.416

  1. Spearman correlation coefficients (rs) with statistical significance (praw and pFDR)