Table 6 Genotype and allele frequency distribution of the four loci of THP-2 between two groups
Locus | Genotype (%) | χ 2 | P | Allele (%) | χ 2 | P | |||
|---|---|---|---|---|---|---|---|---|---|
rs4570625 | GG | GT | TT | 4.525 | 0.104 | G | T | 1.729 | 0.189 |
ODD | 27 (23.3) | 51 (44.0) | 38 (32.8) | 105 (45.3) | 127 (54.7) | ||||
Control | 36 (23.7) | 83 (54.6) | 33 (21.7) | 155 (51.0) | 149 (49.0) | ||||
rs11178997 | AA | AT | TT | 1.092 | 0.579 | A | T | 0.783 | 0.376 |
ODD | 6 (4.9) | 33 (26.8) | 84 (68.3) | 45 (18.3) | 201 (81.7) | ||||
Control | 4 (2.6) | 39 (25.7) | 109 (71.7) | 47 (15.5) | 257 (84.5) | ||||
rs1386494 | AA | AG | GG | 4.163 | 0.041* | A | G | 3.930 | 0.047* |
ODD | 0 | 8 (6.5) | 116 (93.5) | 8 (3.2) | 240 (96.8) | ||||
Control | 0 | 21 (14.1) | 128 (85.9) | 21 (7.0) | 277 (93.0) | ||||
rs7305115 | AA | AG | GG | 0.756 | 0.685 | A | G | 0.780 | 0.377 |
ODD | 34 (28.6) | 56 (47.1) | 29 (24.4) | 124 (52.1) | 114 (47.9) | ||||
Control | 35 (25.2) | 64 (46.0) | 40 (28.8) | 134 (48.2) | 144 (51.8) | ||||