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Table 8 Haplotype analysis of TPH-2 between two groups

From: Association of tryptophan hydroxylase-2 polymorphisms with oppositional defiant disorder in a Chinese Han population

Haplotype distribution

Case (freq)

Control (freq)

χ 2

Fisher P

OR [95% CI]

SNP1-2

 G-A

1.52 (0.007)

10.57 (0.042)

6.281

0.012233*

0.149 [0.027–0.826]

 T-A

40.48 (0.174)

24.43 (0.098)

6.083

0.013679*

1.951 [1.140–3.341]

SNP1-2-3

 G-A-G

1.51 (0.007)

10.51 (0.042)

6.234

0.012562*

0.149 [0.027–0.831]

 T-A-G

38.73 (0.167)

24.00 (0.096)

5.409

0.020075*

1.896 [1.099–3.272]

SNP1-2-4

 T-A-A

22.24 (0.096)

10.60 (0.042)

4.981

0.025669*

2.315 [1.088–4.927]

SNP1-2-3-4

 T-A-G-A

21.77 (0.094)

7.79 (0.031)

8.031

0.004617*

3.187 [1.376–7.382]

  1. SNP1:rs4570625; SNP2:rs11178997; SNP3:rs1386494; SNP4:rs7305115 * P<0.05
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Behavioral and Brain Functions

ISSN: 1744-9081

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