Fig. 3

Effects of SBF on memory acquisition and re-learning impairment induced by composited Aβ in rats. The positioning navigation trial was used to evaluate memory acquisition by 2 consecutive days swimming achievement on day 1 and 2 in the Morris water maze test. These were performed on day 31 and 32 after initiation of treatment with SBF, which corresponded to day 79 and 80 after the operation. The reversal trial was used to evaluate memory re-learning of rats by 3 consecutive days swimming score on day 4, 5, and 6 in the Morris water maze test, which corresponded to day 34, 35 and 36 of SBF treatment, namely on day 82, 83 and 84 after the operation. The line graph plots showed the mean latency to find the hidden platform for each group on day 1, 2, 4, 5, and 6 in the Morris water maze test. Data were analyzed by two-way ANOVA (day × group) with repeated measures. Mean ± SEM. n = 6. ^## P < 0.01, vs. sham-operated group. **P < 0.01, vs. composited Aβ-treated group