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Fig. 5 | Behavioral and Brain Functions

Fig. 5

From: Scutellaria barbata flavonoids alleviate memory deficits and neuronal injuries induced by composited Aβ in rats

Fig. 5

Effects of SBF on pathological changes in the hippocampus and cerebral cortex induced by composited Aβ in rats. Representative images of hippocampal and cerebral cortical neurons stained with HE. A1E1 Hippocampus ×40; A2E2 Hippocampus CA1 ×400; A3E3 Cerebral cortex ×400. A1A3 Sham-operated group; B1B3 Composited Aβ-treated group; showing loss of neurons, neurofibrillary degeneration (→), neuronophagia (←), nuclear pyknosis (), nuclear margination (), colliquative necrosis ()with disrupted cellular membranes. Nuclei were fragmented, and large numbers of inflammatory cells infiltrated regions of the cerebral cortex in composited Aβ-treated rats. C1C3 SBF 35 mg/kg group; D1D3 SBF 70 mg/kg group; E1E3 SBF 140 mg/kg group. Scale bar 10 or 100 µm

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