Fig. 4
From: Differential responses of stressful elements to predatory exposure in behavior-lateralized mice
The expression of GR in the hippocampus of behavior-lateralized mice after predatory exposure (8 mice in each group). a Influence of predatory exposure on the expression of GR mRNA. The GR mRNA expression in the hippocampus was downregulated profoundly after acute stress and chronic stress. The normal control group (without considering behavioral lateralization) was used as the calibrator for normalization (*P < 0.05, **P < 0.01, ***P < 0.001). b, c The expression of GR mRNA in the hippocampus of behavior-lateralized mice after predatory stress. Acute and chronic stress reduced the GR mRNA expression significantly, particularly in the left-pawed mice. For the normal control group, the GR mRNA in the left and right hippocampus of the left-pawed mice was higher than that of the right-pawed mice. The normal control group (without considering behavioral lateralization) was used as the calibrator for normalization (*P < 0.05, **P < 0.01, ***P < 0.001). d–h The expression of the GR protein in the hippocampus of behavior-lateralized mice after predatory exposure. The acute and chronic stress decreased the GR protein expression in the left and right hippocampus of both right-pawed and left-pawed mice (relative density: *P < 0.05). Lc left-pawed mice in control group, Las left-pawed mice in acute stress group, Lcs left-pawed mice in chronic stress group, Rc right-pawed mice in control group, Ras right-pawed mice in acute stress group, Rcs right-pawed mice in chronic stress group