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Fig. 3 | Behavioral and Brain Functions

Fig. 3

From: Reversal of reserpine-induced depression and cognitive disorder in zebrafish by sertraline and Traditional Chinese Medicine (TCM)

Fig. 3

Exploratory profiles of zebrafish exposed to sertraline and JWXY capsule after reserpine treatment in the novel tank test. a Diagram of the exploratory behaviours recorded by a camera from a lateral view. The histograms demonstrated the exploratory behaviours of adult zebrafish by the b average entry duration to the top, c distance travelled in the top, d time spent in the top, e time spent top: bottom ratio, f distance travelled top: bottom, g latency to enter the top and h entries top: bottom ratio. Control: untreated AB strain zebrafish. Acute: acute treatment with reserpine for 20 min. Model: after acute treatment with reserpine, zebrafish were exposed to system water for 7 days to generate the depression model. Sertraline: after acute treatment with reserpine, zebrafish were exposed to sertraline for 7 days. JWXY: after acute treatment with reserpine, zebrafish were exposed to JWXY capsule for 7 days. The data are expressed as the mean ± S.E.M. and were analysed by one-way ANOVA followed by the Tukey post hoc test. Significance was defined as *p < 0.05, **p < 0.01

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