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Table 2 Comparison of the results with elevated plus maze test obtained before and after social defeat stress among three groups

From: Effects of social defeat stress on dopamine D2 receptor isoforms and proteins involved in intracellular trafficking

Parameters

Control group (n = 12)

p a

Unsusceptible group (n = 16)

p a

Susceptible group (n = 34)

p a

p b

Before

After

Change

Before

After

Change

Before

After

Change

Time spent in arms (s)

 Open arm

39.90 ± 6.36

18.89 ± 4.90

− 21.01 ± 7.72

0.020

32.77 ± 4.70

10.38 ± 3.08

− 22.38 ± 5.83

0.003

53.12 ± 4.95

5.93 ± 1.66

− 47.18 ± 4.97*†

< 0.001

0.002

 Closed arm

212.43 ± 8.54

249.29 ± 9.48

36.85 ± 12.04

0.011

221.55 ± 6.68

270.98 ± 4.72

49.42 ± 8.79

< 0.001

199.25 ± 5.28

277.99 ± 2.83

78.74 ± 5.84*

< 0.001

0.002

Number of entries

 Open arm

6.16 ± 1.02

2.33 ± 0.52

− 3.83 ± 1.19

0.008

7.09 ± 1.54

1.54 ± 0.65

− 5.54 ± 0.85

< 0.001

7.00 ± 0.55

1.03 ± 0.24

− 5.96 ± 0.58

< 0.001

0.275

 Closed arm

14.91 ± 1.00

16.25 ± 1.23

1.33 ± 2.11

0.541

16.90 ± 1.58

11.0 ± 1.09

− 5.90 ± 1.86*

0.010

15.5 ± 0.61

9.25 ± 0.78

− 6.25 ± 0.99*

< 0.001

0.002

  1. Data expressed as mean ± S.E.M
  2. aStudent’s paired t test between the data obtained before and after social defeat stress
  3. bOne-way ANOVA for the change
  4. * p < 0.05 versus control group
  5. †p < 0.05 versus unsusceptible group