Fig. 1

Effects of early maternal immune activation on prepulse inhibition in rat offspring. Data are shown as mean ± SEM. N = 10 for each group. a Maternal immune activation produced no significant differences in any dB group (70, 75, or 80 dB) in adolescence. b Prepulse inhibition defects were observed in all dB groups (70, 75, and 80 dB) in adult offspring of dams exposed to Poly I:C at gestational day 9. ***P < 0.001