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Fig. 7 | Behavioral and Brain Functions

Fig. 7

From: Age-related changes in neuroinflammation and prepulse inhibition in offspring of rats treated with Poly I:C in early gestation

Fig. 7

Effects of early maternal immune activation (MIA) on cytokines (IL-1β, IL-6, and TNF-α) in the prefrontal cortex (PFC) and hippocampus (HC) regions of MIA rat offspring during adolescence and adulthood. Overall, most of these cytokines behaved in region- and age-related manners. Data are shown as mean ± SEM; n = 8 for Poly I:C group, n = 7 for vehicle group. ac Concentrations (pg/mg) of IL-1β, IL-6, and TNF-α in the PFC during adolescence and adulthood. df Concentrations (pg/mg) of IL-1β, IL-6, and TNF-α in the HC during adolescence and adulthood. *P < 0.05

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