Table 1 Definitions of important terms found in fly AUD research
From: Studying alcohol use disorder using Drosophila melanogaster in the era of ‘Big Data’
Term: | Definition |
|---|---|
ChIP-seq | Chromatin immunoprecipitation sequencing |
GWAS | Genome wide association studies (also known as WGA—whole genome association) |
MB | Mushroom body; an important neural center in flies; involved in olfaction and olfactory memory formation |
NGS | Next generation sequencing (massive parallel sequencing) |
RNA-seq | RNA sequencing (whole genome RNA sequencing) |
SNP | Single nucleotide polymorphism |
Wildtype | Aa model strain of organism fly with no induced mutations |
RNAi | Short hairpin RNA used to target RNA for degradation. Used to knockdown expression of genes |
Behavioral assays: terms | |
booz-o-mat | Aa horizontal assay for intoxicating flies |
Inebriometer | Aa vertical assay for intoxicating flies |
CAFE | Ccapillary feeding assay |
PER | Pproboscis extension reflex; used to study alcohol’s appetitive properties |