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Fig. 4 | Behavioral and Brain Functions

Fig. 4

From: Sexual dimorphism in cognitive disorders in a murine model of neuropathic pain

Fig. 4

SNT impaired spatial learning memory in male mice but not in female mice. SNT-injured male mice (a), but not female mice (b), required more time to escape onto the hidden platform compared with the sham group. Performances of sham and SNT-injured male (cf) and female (gj) mice in a Morris water maze probe trial. Time spent and swimming distance in the target quadrant were recorded. The total distance did not differ between the sham and SNT groups on the probe test. Data are presented as the mean ± SEM., male: n = 12 for sham, n = 12 for SNT; female: n = 12 for sham, n = 12 for SNT. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the sham group

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