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Fig. 1 | Behavioral and Brain Functions

Fig. 1

From: Susceptibility to chronic immobilization stress‐induced depressive-like behaviour in middle‐aged female mice and accompanying changes in dopamine D1 and GABAA receptors in related brain regions

Fig. 1

Chronic immobilization stress (CIS)-induced susceptibility to depressive-like behaviour in middle-aged mice. The data are presented as the mean ± SEM. a Forced swim test (FST). b Tail suspension test (TST). c Sucrose preference test (SPT). Age could not directly induce depressive-like behaviour in mice in the absence of stress. However, age could increase the susceptibility to depressive-like behaviour in middle-aged mice upon exposure to CIS (n = 8–10 per group). *P < 0.05 compared with the age-matched control group; #P < 0.05 compared with young mice subjected to the same treatment; + P < 0.05 compared with the pre-test data of the same group. Differences among the four groups were analysed by two-way analysis of variance (ANOVA) followed by the LSD post hoc multiple comparisons test. Differences between pre-test and test data in the SPT were analysed by independent-samples t test

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Behavioral and Brain Functions

ISSN: 1744-9081

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