Fig. 2From: Susceptibility to chronic immobilization stress‐induced depressive-like behaviour in middle‐aged female mice and accompanying changes in dopamine D1 and GABAA receptors in related brain regionsChanges in the mRNA level of DRD1 in the nucleus accumbens (NAc) and prefrontal cortex (PFC). The data are presented as the mean ± SEM. a DRD1 expression in the NAc. b DRD1 expression in the PFC. Age could directly induce a decrease in the mRNA level of DRD1 in the NAc and PFC in mice in the absence of stress. A further decrease in the mRNA level of DRD1 in the NAc was found in middle-aged mice upon exposure to CIS. *P < 0.05 compared with the age-matched control group; # P < 0.05 compared with young mice subjected to the same treatment. Two-way ANOVA followed by the LSD post hoc multiple comparisons testBack to article page