Skip to main content
Fig. 2 | Behavioral and Brain Functions

Fig. 2

From: Susceptibility to chronic immobilization stress‐induced depressive-like behaviour in middle‐aged female mice and accompanying changes in dopamine D1 and GABAA receptors in related brain regions

Fig. 2

Changes in the mRNA level of DRD1 in the nucleus accumbens (NAc) and prefrontal cortex (PFC). The data are presented as the mean ± SEM. a DRD1 expression in the NAc. b DRD1 expression in the PFC. Age could directly induce a decrease in the mRNA level of DRD1 in the NAc and PFC in mice in the absence of stress. A further decrease in the mRNA level of DRD1 in the NAc was found in middle-aged mice upon exposure to CIS. *P < 0.05 compared with the age-matched control group; # P < 0.05 compared with young mice subjected to the same treatment. Two-way ANOVA followed by the LSD post hoc multiple comparisons test

Back to article page