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Fig. 6 | Behavioral and Brain Functions

Fig. 6

From: Distinct behavioral traits and associated brain regions in mouse models for obsessive–compulsive disorder

Fig. 6

The c-fos expression in the brain of 8-OH-DPAT-treated mice. a Representative immunofluorescence micrographs depicting the c-fos expression levels in the ACC, PrL, IL, OFC, AcbSh, and hypothalamus. Expression levels were increased in 8-OH-DPAT-treated mice compared with saline-treated control mice, whereas c-fos expression levels in the Acbc and CPu were not significantly different (Scale bars: 100 μm). b Quantification of the c-fos expression in the OFC, PrL, IL, ACC, CPu, NAc, and hypothalamus in 8-OH-DPAT and saline-treated mice. Data are expressed as the mean ± SEM. Unpaired t-test: ***p < 0.001, ****p < 0.0001

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