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Fig. 2 | Behavioral and Brain Functions

Fig. 2

From: Effect of combination fluoxetine and exercise on prefrontal BDNF, anxiety-like behavior and fear extinction in a female rat model of post-traumatic stress disorder (PTSD): a comparison with male animals

Fig. 2

Prefrontal cortex (A), and serum BDNF (B) in female SPS and sham groups subjected to fluoxetine and treadmill exercise. SPS groups showed reductions in serum and prefrontal cortex BDNF. SPS groups with fluoxetine & treadmill exercise showed increased in serum and Prefrontal cortex BDNF as compared with SPS sedentary groups. A *SPS/SED-VEH vs sham/SED-VEH (P = 0.001). **sham/EXE-VEH (P = 0.014) and sham/FLX –EXC (P = 0.0001) vs sham/SED-VEH. ***sham/FLX-SED and sham/EXE-VEH (P = 0.0001) vs sham/FLX –EXC. ****SPS/SED-VEH vs SPS/EXC-FLX (P = 0.0001), SPS/EXC-VEH (P = 0. 001), SPS/SED-FLX (P = 0.003). *****SPS/EXC-FLX vs sham/FLX –EXC (P = 0.0001). B *SPS/EXC-VEH (P = 0.015) and SPS/EXC-FLX (P = 0.012) vs SPS/SED-VEH

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