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Fig. 7 | Behavioral and Brain Functions

Fig. 7

From: Pristane induced lupus mice as a model for neuropsychiatric lupus (NPSLE)

Fig. 7

Density and morphology of microglia and astrocytes in the hippocampus. A Representative images of the hippocampus stained with H&E. B, C Representative images showing Iba-1-immunoreactive microglia and GFAP-immunoreactive astrocytes in the hippocampus. DAPI staining of nuclei (blue). White square showing an enlarged cell to compare morphology. D, E Quantitative analysis of the density of Iba-1-immunoreactive cells (p < 0.0001, < 0.0001, < 0.0001) and GFAP-immunoreactive cells (p < 0.0001, 0.5512, 0.3670). The data are expressed as the mean ± SEM (n = 12 in each group). Two-way ANOVA followed by Tukey’s post hoc test or Scheirer–Ray–Hare test: **p < 0.01

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