Fig. 5
From: Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
NLRP1-siRNA treatment ameliorates learning and memory impairments in APP/PS1 mice (Morris water maze, MWM). A The mean escape latency (MEL, s) in the orientation navigation test; B The track of MWM in APP/PS1 mice in the probe test; C The swimming time in the quadrant of platform (STP, s); D The number of crossing the platform (NCP); E The latency of first entry to the platform (LFP, s). Results are expressed as mean ± SD, n = 8. *P < 0.05 vs NS group