Fig. 7
From: Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
NLRP1-siRNA treatment reduces Aβ generation in APP/PS1 mice (Western blot). A The bands of APP, Aβ1-42, BACE1, CTF-β, NCSTN and β-actin; B The relative expression of APP over NS; C The relative expression of Aβ1-42 over NS; D The relative expression of BACE1 over NS; E The relative expression of CTF-β over NS; F The relative expression of NCSTN over NS. G The relative mRNA expression of APP (q-PCR); H The relative mRNA expression of BACE1 (q-PCR); I The relative mRNA expression of NCSTN (q-PCR). Results are expressed as mean ± SD, n = 4. *P < 0.05, **P < 0.01 vs NS