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Fig. 8 | Behavioral and Brain Functions

Fig. 8

From: Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice

Fig. 8

NLRP1-siRNA treatment reduces Aβ deposition in APP/PS1 mice. A The Aβ deposition in cortex (Thioflavin-S staining, 200× , bar = 50 μm; 400× , bar = 20 μm, exposure time: 200 ms); B The density of Aβ deposition. C The expression of Aβ1-42 in cortex (immunofluorescence 200× , bar = 50 μm; 400× , bar = 20 μm, exposure time:150 ms); D The expression of Aβ1-42. Results are expressed as mean ± SD, n = 4. **P < 0.01 vs NS group

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