Fig. 9
From: Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
NLRP1-siRNA treatment inhibits NLRP1 inflammasome activation in APP/PS1 mice. A The bands of NLRP1, ASC, caspase-1, IL-1β, NF-κB, p-NF-κB and β-actin (Western blot); B The relative expression of NLRP1 over NS; C The relative expression of ASC over NS; D The relative expression of caspase-1 over NS; E The relative expression of IL-1β over NS. F The relative expression of NF-κB over NS; G The relative expression of p-NF-κB over NS. H The relative mRNA expression of NLRP1 (q-PCR); I The relative mRNA expression of ASC (q-PCR); J The relative mRNA expression of Caspase-1 (q-PCR); K The relative mRNA expression of IL-1β (q-PCR). Results are expressed as mean ± SD, n = 4. *P < 0.05, **P < 0.01 vs NS group