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Fig. 4 | Behavioral and Brain Functions

Fig. 4

From: Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice

Fig. 4

Basic synaptic transmission decreased in the dorsal hippocampus at 7 months after intra-hippocampal cis P-tau injection. Graphs show the basic synaptic transmission (I–O curve) A and test pulse intensity B in the dorsal vs. ventral hippocampal slices in the control group. Cis P-tau injection shifted the I-O curve to the right C and decreased the test pulse intensity D in the dorsal hippocampus in the cis P-tau compared to the control group. In the ventral hippocampal slices no significant difference observed in I-O curve E and test pulse intensity F between cis P-tau compared to the control group. All data represent mean ± SEM. * P < 0.05

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