Table 1 Clinical description and demographics of subjects groups
From: Number of risk genotypes is a risk factor for major depressive disorder: a case control study
Subject term | Descriptive clinical information | N | % female | Mean years of age (range) |
|---|---|---|---|---|
Depressed | Combination of Non-responders and responders (see below) | 97 | 66.7% | 46.7 (24–72) |
Non-responders (treatment resistant depression) | Clinical diagnosis of chronic or recurrent depression and failure to achieve remission after at least two adequate antidepressant trials as documented by the Antidepressant Treatment History Form (ATHF). | 58 | 61% | 47.2 (24–65) |
Responders | Clinical diagnosis of major depressive disorder, and capability to respond to standard antidepressant medication. | 39 | 75% | 46.1 (25–72) |
Controls | Subjects who denied a personal history of mental illness based on the mood disorders section of the Structured Questionnaire Interview for DSM-IV-R (SCID) questionnaire. | 85 | 64.3% | 23.1 (18–68) |