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  1. Research

    The social brain network in 22q11.2 deletion syndrome: a diffusion tensor imaging study

    Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a neurogenetic disorder that is associated with a 25-fold increase in schizophrenia. Both individuals with 22q11.2DS and those with schizophrenia present wit...

    Amy K. Olszewski, Zora Kikinis, Christie S. Gonzalez, Ioana L. Coman, Nikolaos Makris, Xue Gong, Yogesh Rathi, Anni Zhu, Kevin M. Antshel, Wanda Fremont, Marek R. Kubicki, Sylvain Bouix, Martha E. Shenton and Wendy R. Kates

    Behavioral and Brain Functions 2017 13:4

    Published on: 16 February 2017

  2. Research

    Logical fallacies in animal model research

    Animal models of human behavioural deficits involve conducting experiments on animals with the hope of gaining new knowledge that can be applied to humans. This paper aims to address risks, biases, and fallaci...

    Espen A. Sjoberg

    Behavioral and Brain Functions 2017 13:3

    Published on: 15 February 2017

  3. Research

    Mothers’ pupillary responses to infant facial expressions

    Human parental care relies heavily on the ability to monitor and respond to a child’s affective states. The current study examined pupil diameter as a potential physiological index of mothers’ affective respon...

    Santeri Yrttiaho, Dana Niehaus, Eileen Thomas and Jukka M. Leppänen

    Behavioral and Brain Functions 2017 13:2

    Published on: 6 February 2017

  4. Research

    Scutellaria barbata flavonoids alleviate memory deficits and neuronal injuries induced by composited Aβ in rats

    The aim of the present study was to investigate the effects of Scutellaria barbata flavonoids (SBF) on memory impairment and neuronal injury induced by amyloid beta protein 25–35 in combination with aluminum tric...

    Xiao G. Wu, Shu S. Wang, Hong Miao, Jian J. Cheng, Shu F. Zhang and Ya Z. Shang

    Behavioral and Brain Functions 2016 12:33

    Published on: 8 December 2016

  5. Research

    Venlafaxine ameliorates the depression-like behaviors and hippocampal S100B expression in a rat depression model

    Accumulating evidence has indicated that S100B may be involved in the pathophysiology of depression. No published study has examined the effect of the antidepressant drug venlafaxine on S100B in animal models ...

    Chang-Hong Wang, Jing-Yang Gu, Xiao-Li Zhang, Jiao Dong, Jun Yang, Ying-Li Zhang, Qiu-Fen Ning, Xiao-Wen Shan and Yan Li

    Behavioral and Brain Functions 2016 12:34

    Published on: 8 December 2016

  6. Research

    A functional magnetic resonance imaging investigation of visual hallucinations in the human striate cortex

    Human beings frequently experience fear, phobia, migraine and hallucinations, however, the cerebral mechanisms underpinning these conditions remain poorly understood. Towards this goal, in this work, we aim to...

    Hina Abid, Fayyaz Ahmad, Soo Y. Lee, Hyun W. Park, Dongmi Im, Iftikhar Ahmad and Safee U. Chaudhary

    Behavioral and Brain Functions 2016 12:31

    Published on: 29 November 2016

  7. Research

    Association of tryptophan hydroxylase-2 polymorphisms with oppositional defiant disorder in a Chinese Han population

    Oppositional defiant disorder (ODD) is a behavioral disorder of school-age population. It is well known that 5-HT dysfunction is correlated with impulsivity, which is one of the common characteristics of ODD. ...

    Chang-Hong Wang, Cong Liu, En-Zhao Cong, Gai-Ling Xu, Ting-Ting Lv, Ying-Li Zhang, Qiu-Fen Ning, Ji-Kang Wang, Hui-Yao Nie and Yan Li

    Behavioral and Brain Functions 2016 12:30

    Published on: 21 November 2016

  8. Review

    The role of C957T, TaqI and Ser311Cys polymorphisms of the DRD2 gene in schizophrenia: systematic review and meta-analysis

    The association between the dopamine D2 receptor (DRD2) gene and schizophrenia has been studied though no conclusive outcomes have been attained. The aim of this study was to perform a systematic review and meta-...

    Thelma Beatriz González-Castro, Yazmín Hernández-Díaz, Isela Esther Juárez-Rojop, María Lilia López-Narváez, Carlos Alfonso Tovilla-Zárate, Alma Genis-Mendoza and Mariela Alpuin-Reyes

    Behavioral and Brain Functions 2016 12:29

    Published on: 9 November 2016

  9. Research

    Age, environment, object recognition and morphological diversity of GFAP-immunolabeled astrocytes

    Few studies have explored the glial response to a standard environment and how the response may be associated with age-related cognitive decline in learning and memory. Here we investigated aging and environme...

    Daniel Guerreiro Diniz, Marcus Augusto de Oliveira, Camila Mendes de Lima, César Augusto Raiol Fôro, Marcia Consentino Kronka Sosthenes, João Bento-Torres, Pedro Fernando da Costa Vasconcelos, Daniel Clive Anthony and Cristovam Wanderley Picanço Diniz

    Behavioral and Brain Functions 2016 12:28

    Published on: 10 October 2016

  10. Research

    A non-targeted metabolite profiling pilot study suggests that tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs

    Attention deficit hyperactivity disorder (ADHD) is a prevalent and multifactorial neuropsychiatric disorder in the human population worldwide. Complex etiology and clinical heterogeneity have challenged the re...

    Jenni Puurunen, Sini Sulkama, Katriina Tiira, Cesar Araujo, Marko Lehtonen, Kati Hanhineva and Hannes Lohi

    Behavioral and Brain Functions 2016 12:27

    Published on: 29 September 2016

  11. Research

    Relationship among methadone dose, polymorphisms of dopamine D2 receptor and tri-dimensional personality questionnaire in heroin-addicted patients

    We investigated whether variation in the dopamine D2 receptor gene (DRD2) and tri-dimensional personality questionnaire (TPQ) scores could be used to aid adjustment of daily methadone requirements of heroin addic...

    Min-Wei Huang, Tai-An Chiang, Pei-Yu Lo and Ching-Shan Huang

    Behavioral and Brain Functions 2016 12:24

    Published on: 31 August 2016

  12. Research

    Transgenerational effects of paternal heroin addiction on anxiety and aggression behavior in male offspring

    Heroin addiction is a growing concern, affecting the socioeconomic development of many countries. Little is known about transgenerational effects on phenotype changes due to heroin addiction. This study aims t...

    Mohd Zaki Farah Naquiah, Richard Johari James, Suraya Suratman, Lian Shien Lee, Mohd Izhar Mohd Hafidz, Mohd Zaki Salleh and Lay Kek Teh

    Behavioral and Brain Functions 2016 12:23

    Published on: 31 August 2016

  13. Research

    Associations between the neuron-specific glucocorticoid receptor (NR3C1) Bcl-1 polymorphisms and suicide in cancer patients within the first year of diagnosis

    Cancer diagnosis is associated with an increased suicide risk, particularly within the first 1 year after diagnosis of cancer. Abnormal function of the hypothalamic–pituitary–adrenal axis has been implicated i...

    Subin Park, Jin Pyo Hong, Jong-Keuk Lee, Young-Mi Park, Yangsoon Park, Juri Jeon, Myeong Hee Ahn and Se Chang Yoon

    Behavioral and Brain Functions 2016 12:22

    Published on: 11 July 2016

  14. Research

    Association between C3435T polymorphism of MDR1 gene and the incidence of drug-resistant epilepsy in the population of Polish children

    Epilepsy is a disease of neurological character. Approximately one third of epileptic patients demonstrate a drug-resistant phenotype, which is associated with the development of drug-resistant epilepsy. The m...

    Mariusz Stasiołek, Hanna Romanowicz, Katarzyna Połatyńska, Maciej Chamielec, Dominik Skalski, Marianna Makowska and Beata Smolarz

    Behavioral and Brain Functions 2016 12:21

    Published on: 8 July 2016

  15. Research

    The effect of epilepsy on autistic symptom severity assessed by the social responsiveness scale in children with autism spectrum disorder

    As the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970–1977, 2005), it is speculated that there is a special relationship between the two...

    Chanyoung Ko, Namwook Kim, Eunjoo Kim, Dong Ho Song and Keun-Ah Cheon

    Behavioral and Brain Functions 2016 12:20

    Published on: 27 June 2016

  16. Research

    Developmental stress elicits preference for methamphetamine in the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder

    Developmental stress has been hypothesised to interact with genetic predisposition to increase the risk of developing substance use disorders. Here we have investigated the effects of maternal separation-induc...

    Jacqueline S. Womersley, Bafokeng Mpeta, Jacqueline J. Dimatelis, Lauriston A. Kellaway, Dan J. Stein and Vivienne A. Russell

    Behavioral and Brain Functions 2016 12:18

    Published on: 17 June 2016

  17. Research

    Chronic cigarette smoking is linked with structural alterations in brain regions showing acute nicotinic drug-induced functional modulations

    Whereas acute nicotine administration alters brain function which may, in turn, contribute to enhanced attention and performance, chronic cigarette smoking is linked with regional brain atrophy and poorer cogn...

    Matthew T. Sutherland, Michael C. Riedel, Jessica S. Flannery, Julio A. Yanes, Peter T. Fox, Elliot A. Stein and Angela R. Laird

    Behavioral and Brain Functions 2016 12:16

    Published on: 2 June 2016

  18. Review

    Safety out of control: dopamine and defence

    We enjoy a sophisticated understanding of how animals learn to predict appetitive outcomes and direct their behaviour accordingly. This encompasses well-defined learning algorithms and details of how these mig...

    Kevin Lloyd and Peter Dayan

    Behavioral and Brain Functions 2016 12:15

    Published on: 23 May 2016

  19. Research

    Oral administration of potassium bromate induces neurobehavioral changes, alters cerebral neurotransmitters level and impairs brain tissue of swiss mice

    Potassium bromate (KBrO3) is widely used as a food additive and is a major water disinfection by-product. The present study reports the side effects of KBrO3 administration on the brain functions and behaviour of...

    Jamaan Ajarem, Naif G. Altoom, Ahmed A. Allam, Saleh N. Maodaa, Mostafa A. Abdel- Maksoud and Billy KC. Chow

    Behavioral and Brain Functions 2016 12:14

    Published on: 12 May 2016

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