Transgenic mice expressing constitutive active MAPKAPK5 display gender-dependent differences in exploration and activity

Table 1 Overview of defensive behaviour of mice during background breeding.

FNTG: Female non-transgenic littermates FTG: Female transgenic mice; MNTG: Male non-transgenic littermates; MTG: Male transgenic mice. As parameters for defensive behaviour we listed vocalization, provoked biting and jump attacks. We monitored the presence (1) or absence (0) of vocalization and biting during handling and if the mice performed a jump attack (0/1). For each parameter vocalization, biting and jump attack, the number represents the number of mice that vocalized, bit or jumped, whereas the population size represents the total number of tested animals. "TG-NTG" indicates the difference between TG and NTG mice respectively. "Standard P" or the probability level α represents the probability that the same event happens at random and "P_rep", the likelihood that the event occurs in a new experiment. The association value represents whether the two distributions are dependent on each other.

ISSN: 1744-9081