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Table 4 Results from univariate logistic regression analysis i.e., OR, 95% CI, Wald statistic, and probability values for predictor variables of MDD suicide behaviors

From: Effect of Tryptophan Hydroxylase-2 rs7305115 SNP on suicide attempts risk in major depression

Variables

OR

95% CI

Wald

P value

Education under middle school

2.39

1.62-3.52

19.705

0.000

Married

0.20

0.12-0.32

46.600

0.000

Age of onset (= ≥ 35 years)

0.79

0.54-1.17

1.407

0.236

Short course of diseases (= ≤ 1 year)

0.83

0.57-1.21

0.943

0.332

Employed

0.67

0.45-1.00

3.809

0.051

Family history of Mental illness

0.94

0.64-1.39

0.086

0.769

Onset abruptly or subacute

1.13

0.76-1.68

0.366

0.545

Predisposing factors

1.15

0.78-1.72

0.500

0.479

Unhappy childhood

1.12

0.70-1.80

0.233

0.650

Family history of suicide

2.58

1.47-4.54

11.328

0.001

Physical disease

1.15

0.69-1.93

0.279

0.597

Monthly income (= < $40)

2.02

1.37-2.99

7.892

0.005

Smoking

1.64

1.02-2.65

4.164

0.041

Drinking

1.64

1.07-2.53

5.178

0.023

Introversion

1.90

1.25-2.87

9.155

0.002

Economic pressure

2.58

1.64-4.05

17.434

0.000

Unhappy a month ago

0.96

0.65-1.42

0.040

0.841

Unhappy a year ago

1.14

0.76-1.72

0.397

0.529

Unhappy after a year

0.87

0.60-1.31

0.362

0.547

Friend suicide two weeks ago

1.11

0.46-2.66

0.050

0.823

Friend suicide a year ago

1.22

0.60-2.49

0.295

0.587

Negative life events half year ago

5.74

3.28-10.04

43.365

0.000

Family emotional support needed

0.43

0.26-0.72

10.587

0.001

Family emotional support gained

1.06

0.72-1.55

0.086

0.769

Friends' emotional support needed

0.38

0.24-0.60

16.025

0.000

Friends' emotional support gained

1.06

0.72-1.55

0.084

0.772

Depression (HDRS = ≥ 35) a

1.58

1.07-2.34

5.227

0.020

Hopelessness (HDRS = ≥ 6) a

7.68

4.99-11.83

93.755

0.000

Anxiety/Somatization(HDRS = > 7) a

0.84

0.56-1.27

0.706

0.401

Loss of weight in a week(= 0.5 kg)

0.93

0.64-1.36

0.149

0.699

Cognitive impairment(HDRS = > 12) a

1.17

0.77-1.78

0.553

0.457

Diurnal change (HDRS = ≥ 1) a

1.12

0.76-1.66

0.350

0.554

Slow movement (HDRS = ≥ 8) a

1.12

1.77-4.64

0.340

0.560

Sleep disorders (HDRS = ≥ 2) a

3.28

2.20-4.88

35.128

0.000

Anxiety (HAMA = ≥ 21) b

4.12

2.54-6.68

35.622

0.000

TPH2 rs7305115 AA

0.50

0.31-0.82

13.941

0.000

  1. a HDRS, Hamilton depression rating scale for depression;
  2. b HAMA, Hamilton anxiety scale for anxiety
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Behavioral and Brain Functions

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