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Table 2 Genotype distributions and allele frequencies of each polymorphism of the SYN2 and CPLX2 in the schizophrenia and control groups.

From: Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Polymorphism Subjects Genotype distribution (frequency)   Allele frequency  
   11 12 22 P a 1 2 P b
SYN2-1 Cases (n = 113) 47 (0.416) 50 (0.442) 16 (0.142) 0.527 0.637 0.363 0.679
  Controls (n = 114) 41 (0.360) 59 (0.518) 14 (0.122)   0.618 0.382  
SYN2-2 Cases (n = 113) 40 (0.354) 55 (0.487) 18 (0.159) 0.758 0.597 0.403 0.438
  Controls (n = 114) 36 (0.316) 56 (0.491) 22 (0.193)   0.561 0.439  
SYN2-3 Cases (n = 113) 83 (0.735) 30 (0.265) 0 (0.000) 0.762 0.867 0.133 0.975
  Controls (n = 114) 85 (0.746) 28 (0.246) 1 (0.009)   0.868 0.132  
SYN2-4 Cases (n = 113) 49 (0.434) 45 (0.398) 19 (0.168) 0.722 0.633 0.367 0.612
  Controls (n = 114) 44 (0.386) 51 (0.447) 19 (0.167)   0.610 0.390  
SYN2-5 Cases (n = 113) 72 (0.637) 35 (0.310) 6 (0.053) 0.973 0.792 0.208 0.869
  Controls (n = 114) 74 (0.649) 34 (0.298) 6 (0.053)   0.798 0.202  
SYN2-6 Cases (n = 113) 67 (0.593) 39 (0.345) 7 (0.062) 0.786 0.765 0.235 0.622
  Controls (n = 114) 63 (0.553) 44 (0.386) 7 (0.061)   0.746 0.254  
SYN2-7 Cases (n = 113) 39 (0.345) 54 (0.478) 20 (0.177) 0.847 0.584 0.416 0.576
  Controls (n = 114) 42 (0.368) 55 (0.482) 17 (0.149)   0.610 0.390  
CPLX2-1 Cases (n = 154) 132 (0.857) 22 (0.143) 0 (0.000) 0.441 0.929 0.071 0.612
  Controls (n = 133) 113 (0.850) 18 (0.135) 2 (0.015)   0.917 0.083  
CPLX2-2 Cases (n = 154) 132 (0.857) 22 (0.143) 0 (0.000) 0.254 0.929 0.071 0.198
  Controls (n = 133) 108 (0.812) 23 (0.173) 2 (0.015)   0.898 0.102  
CPLX2-3 Cases (n = 154) 115 (0.747) 34 (0.221) 5 (0.032) 0.129 0.857 0.143 0.072
  Controls (n = 133) 85 (0.639) 43 (0.323) 5 (0.038)   0.801 0.199  
CPLX2-4 Cases (n = 154) 110 (0.714) 40 (0.260) 4 (0.026) 1.000 0.844 0.156 0.849
  Controls (n = 133) 94 (0.707) 35 (0.263) 4 (0.030)   0.838 0.162  
CPLX2-5 Cases (n = 154) 124 (0.805) 30 (0.195) 0 (0.000) 0.312 0.903 0.097 0.541
  Controls (n = 133) 112 (0.842) 20 (0.150) 1 (0.008)   0.917 0.083  
  1. a Fisher's exact probability tests, case vs controls (2 × 3 genotype-based analysis)
  2. b Fisher's exact probability tests, case vs controls (2 × 2 allele-based analysis)