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Table 2 Genotype distributions and allele frequencies of each polymorphism of the SYN2 and CPLX2 in the schizophrenia and control groups.

From: Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Polymorphism

Subjects

Genotype distribution (frequency)

 

Allele frequency

 
  

11

12

22

P a

1

2

P b

SYN2-1

Cases (n = 113)

47 (0.416)

50 (0.442)

16 (0.142)

0.527

0.637

0.363

0.679

 

Controls (n = 114)

41 (0.360)

59 (0.518)

14 (0.122)

 

0.618

0.382

 

SYN2-2

Cases (n = 113)

40 (0.354)

55 (0.487)

18 (0.159)

0.758

0.597

0.403

0.438

 

Controls (n = 114)

36 (0.316)

56 (0.491)

22 (0.193)

 

0.561

0.439

 

SYN2-3

Cases (n = 113)

83 (0.735)

30 (0.265)

0 (0.000)

0.762

0.867

0.133

0.975

 

Controls (n = 114)

85 (0.746)

28 (0.246)

1 (0.009)

 

0.868

0.132

 

SYN2-4

Cases (n = 113)

49 (0.434)

45 (0.398)

19 (0.168)

0.722

0.633

0.367

0.612

 

Controls (n = 114)

44 (0.386)

51 (0.447)

19 (0.167)

 

0.610

0.390

 

SYN2-5

Cases (n = 113)

72 (0.637)

35 (0.310)

6 (0.053)

0.973

0.792

0.208

0.869

 

Controls (n = 114)

74 (0.649)

34 (0.298)

6 (0.053)

 

0.798

0.202

 

SYN2-6

Cases (n = 113)

67 (0.593)

39 (0.345)

7 (0.062)

0.786

0.765

0.235

0.622

 

Controls (n = 114)

63 (0.553)

44 (0.386)

7 (0.061)

 

0.746

0.254

 

SYN2-7

Cases (n = 113)

39 (0.345)

54 (0.478)

20 (0.177)

0.847

0.584

0.416

0.576

 

Controls (n = 114)

42 (0.368)

55 (0.482)

17 (0.149)

 

0.610

0.390

 

CPLX2-1

Cases (n = 154)

132 (0.857)

22 (0.143)

0 (0.000)

0.441

0.929

0.071

0.612

 

Controls (n = 133)

113 (0.850)

18 (0.135)

2 (0.015)

 

0.917

0.083

 

CPLX2-2

Cases (n = 154)

132 (0.857)

22 (0.143)

0 (0.000)

0.254

0.929

0.071

0.198

 

Controls (n = 133)

108 (0.812)

23 (0.173)

2 (0.015)

 

0.898

0.102

 

CPLX2-3

Cases (n = 154)

115 (0.747)

34 (0.221)

5 (0.032)

0.129

0.857

0.143

0.072

 

Controls (n = 133)

85 (0.639)

43 (0.323)

5 (0.038)

 

0.801

0.199

 

CPLX2-4

Cases (n = 154)

110 (0.714)

40 (0.260)

4 (0.026)

1.000

0.844

0.156

0.849

 

Controls (n = 133)

94 (0.707)

35 (0.263)

4 (0.030)

 

0.838

0.162

 

CPLX2-5

Cases (n = 154)

124 (0.805)

30 (0.195)

0 (0.000)

0.312

0.903

0.097

0.541

 

Controls (n = 133)

112 (0.842)

20 (0.150)

1 (0.008)

 

0.917

0.083

 
  1. a Fisher's exact probability tests, case vs controls (2 × 3 genotype-based analysis)
  2. b Fisher's exact probability tests, case vs controls (2 × 2 allele-based analysis)
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Behavioral and Brain Functions

ISSN: 1744-9081

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