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Table 3 Pairwise linkage disequilibrium and haplotype association of SNPs in SYN2.

From: Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

  SYN2-1 SYN2-2 SYN2-3 SYN2-4 SYN2-5 SYN2-6 SYN2-7
SYN2-1   0.532 0.776 0.758 0.865 0.516 0.642
   0.222 0.056 0.553 0.306 0.482 0.397
SYN2-2 4.45 × 10 -6 a   0.613 0.453 0.734 0.300 0.429
    0.044 0.250 0.174 0.200 0.225
SYN2-3 0.246 0.632   1.000 0.997 0.480 1.000
     0.097 0.038 0.433 0.097
SYN2-4 0.845 9.12 × 10 -4 a 0.014   1.000 0.480 0.806
      0.395 0.433 0.650
SYN2-5 0.896 0.655 0.135 0.133   0.938 0.865
       0.651 0.295
SYN2-6 0.116 0.892 0.602 0.602 0.147   0.722
        0.278
SYN2-7 0.646 0.044 0.155 0.392 0.404 0.0.72  
  1. Upper diagonal top: D', bottom: r2 in controls; Lower diagonal: P value by χ2 test (df = 3)
  2. a P < 0.05 after Bonferroni correction