Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Table 3 Pairwise linkage disequilibrium and haplotype association of SNPs in SYN2.

	SYN2-1	SYN2-2	SYN2-3	SYN2-4	SYN2-5	SYN2-6	SYN2-7
SYN2-1		0.532	0.776	0.758	0.865	0.516	0.642
		0.222	0.056	0.553	0.306	0.482	0.397
SYN2-2	4.45 × 10 ^{-6 a}		0.613	0.453	0.734	0.300	0.429
			0.044	0.250	0.174	0.200	0.225
SYN2-3	0.246	0.632		1.000	0.997	0.480	1.000
				0.097	0.038	0.433	0.097
SYN2-4	0.845	9.12 × 10 ^{-4 a}	0.014		1.000	0.480	0.806
					0.395	0.433	0.650
SYN2-5	0.896	0.655	0.135	0.133		0.938	0.865
						0.651	0.295
SYN2-6	0.116	0.892	0.602	0.602	0.147		0.722
							0.278
SYN2-7	0.646	0.044	0.155	0.392	0.404	0.0.72

Upper diagonal top: D', bottom: r² in controls; Lower diagonal: P value by χ² test (df = 3)
^a P < 0.05 after Bonferroni correction

ISSN: 1744-9081