Table 1 Summary of Effects of Atomoxetine and Placebo on ADHD Symptoms in Adults*
| Â | Study I | Study II | ||||
|---|---|---|---|---|---|---|
| Â | Placebo (n = 134) | Atomoxetine (n = 133) | p | Placebo (n = 124) | Atomoxetine (n = 124) | p |
CGI Change Score | -0.4 ± 1.0 | -0.8 ± 1.2 | 0.010 | -0.5 ± 1.0 | -0.9 ± 1.2 | 0.002 |
Investigator-Rated CAARS | Â | Â | Â | Â | Â | Â |
   Total ADHD Symptom Scores | -6.0 ± 9.3 | -9.5 ± 10.1 | 0.005 | -6.7 ± 9.3 | -10.5 ± 10.9 | 0.002 |
   Inattentive Score | -3.1 ± 5.8 | -5.0 ± 5.7 | 0.010 | -3.5 ± 5.3 | -5.8 ± 6.5 | 0.001 |
   Hyperactive/Impulsive Score | -2.9 ± 4.9 | -4.5 ± 5.1 | 0.017 | -3.2 ± 4.7 | -4.7 ± 5.3 | 0.013 |
Self-Rated CAARS | Â | Â | Â | Â | Â | Â |
   Total ADHD Symptom Score | -9.3 ± 14.0 | -16.0 ± 16.2 | 0.002 | -11.6 ± 16.1 | -17.3 ± 17.6 | 0.008 |
   Inattentive Score | -8.6 ± 13.8 | -15.9 ± 16.3 | 0.001 | -11.3 ± 16.6 | -17.1 ± 17.9 | 0.012 |
   Hyperactive/Impulsive Score | -7.5 ± 12.1 | -11.9 ± 13.5 | 0.013 | -8.8 ± 13.4 | -12.5 ± 14.1 | 0.025 |