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Table 1 Summary of Effects of Atomoxetine and Placebo on ADHD Symptoms in Adults*

From: Efficacy of atomoxetine in adult attention-Deficit/Hyperactivity Disorder: a drug-placebo response curve analysis

  Study I Study II
  Placebo (n = 134) Atomoxetine (n = 133) p Placebo (n = 124) Atomoxetine (n = 124) p
CGI Change Score -0.4 ± 1.0 -0.8 ± 1.2 0.010 -0.5 ± 1.0 -0.9 ± 1.2 0.002
Investigator-Rated CAARS       
   Total ADHD Symptom Scores -6.0 ± 9.3 -9.5 ± 10.1 0.005 -6.7 ± 9.3 -10.5 ± 10.9 0.002
   Inattentive Score -3.1 ± 5.8 -5.0 ± 5.7 0.010 -3.5 ± 5.3 -5.8 ± 6.5 0.001
   Hyperactive/Impulsive Score -2.9 ± 4.9 -4.5 ± 5.1 0.017 -3.2 ± 4.7 -4.7 ± 5.3 0.013
Self-Rated CAARS       
   Total ADHD Symptom Score -9.3 ± 14.0 -16.0 ± 16.2 0.002 -11.6 ± 16.1 -17.3 ± 17.6 0.008
   Inattentive Score -8.6 ± 13.8 -15.9 ± 16.3 0.001 -11.3 ± 16.6 -17.1 ± 17.9 0.012
   Hyperactive/Impulsive Score -7.5 ± 12.1 -11.9 ± 13.5 0.013 -8.8 ± 13.4 -12.5 ± 14.1 0.025
  1. *Data adapted from Michelson et al., 2003
  2. Data are presented as mean ± standard deviation