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Table 2 Association between SNPs in SLC6A3 and dyslexia using the additive, dominant, genotype, and the recessive models

From: Stuttering candidate genes DRD2 but not SLC6A3 is associated with developmental dyslexia in Chinese population

  SNP Patient Control Crude OR (95%CI) Unadjusted p-value Adjusted OR (95%CI) Adjusted p-value Bonferroni corrected p-value
rs11133762 C Allele 552 629 1   1   
T Allele 386 363 1.222(1.013-1.475) 0.03628 1.232(1.004-1.511) 0.04568 1
CC 158 194 1   1   
CT 236 241 1.2024(0.9121-1.5850) 0.19106664 1.1500(0.8517-1.5527) 0.361697 1
TT 75 61 1.5096(1.0141-2.2474) 0.04246577 1.5575(1.0121-2.3967) 0.043953 1
Dom    1.264(0.972-1.645) 0.08041 1.235(0.9291-1.642) 0.1461 1
Rec    1.357(0.9429-1.954) 0.1002 1.46(0.9799-2.175) 0.06285 1
rs3863145 G Allele 925 974 1   1   
A Allele 37 44 0.8916(0.5778-1.376) 0.604 0.935(0.5856-1.493) 0.7783 1
GG 445 468 1   1   
AG 35 38 0.9687(0.6011-1.5610) 0.89593367 1.0151(0.6043-1.7051) 0.954917 1
AA 1 3 0.3506(0.0364-3.3758) 0.36433775 0.4064(0.0394-4.1922) 0.449521 1
Dom    0.9234(0.5794-1.472) 0.7376 0.9701(0.5851-1.608) 0.9063 1
Rec    0.3514(0.03643-3.39) 0.3658 0.4136(0.0402-4.256) 0.458 1
rs40184 C Allele 734 796 1   1   
T Allele 232 218 1.151(0.9343-1.417) 0.1867 1.127(0.9-1.411) 0.2976 1
CC 281 314 1   1   
CT 172 168 1.1440(0.8763-1.4937) 0.32260995 1.0956(0.8214-1.4613) 0.53434 1
TT 30 25 1.3409(0.7701-2.3350) 0.29988039 1.3203(0.7261-2.4007) 0.362334 1
Dom    1.17(0.9067-1.509) 0.228 1.128(0.8567-1.485) 0.3909 1
Rec    1.277(0.7396-2.204) 0.3804 1.306(0.7249-2.355) 0.3738 1
rs6869645 C Allele 939 987 1   1   
T Allele 27 33 0.8604(0.5137-1.441) 0.5677 0.8694(0.4988-1.515) 0.6214 1
CC 456 478 1   1   
CT 27 31 0.9130(0.5365-1.5539) 0.73717584 0.9431(0.5296-1.6794) 0.842233 1
TT 0 1 NA   NA   
Dom    0.8845(0.5216-1.5) 0.6486 0.9032(0.5099-1.6) 0.7273 1
Rec    NA   NA   
rs40358 A Allele 617 643 1   1   
C Allele 347 375 0.9625(0.7976-1.161) 0.6899 0.9412(0.768-1.154) 0.5595 1
AA 190 199 1   1   
AC 237 245 1.01329(0.7756-1.3235) 0.92355677 0.9603(0.7183-1.2838) 0.784396 1
CC 55 65 0.8862(0.5879-1.3360) 0.56412977 0.8738(0.5617-1.3593) 0.549582 1
Dom    0.9866(0.7644-1.273) 0.9172 0.945(0.7171-1.245) 0.6877 1
Rec    0.8798(0.6-1.29) 0.5123 0.8838(0.5843-1.337) 0.5587 1
rs10052016 A Allele 861 923 1   1   
G Allele 101 93 1.167(0.8654-1.575) 0.3109 1.098(0.7937-1.52) 0.5712 1
AA 385 418 1   1   
AG 91 87 1.1356(0.8206-1.5715) 0.44286861 1.0895(0.7663-1.5492) 0.632995 1
GG 5 3 1.8095(0.4297-7.6209) 0.41883352 1.3168(0.2851-6.0832) 0.724443 1
Dom    1.158(0.8417-1.594) 0.3674 1.098(0.7764-1.552) 0.5977 1
  Rec    1.768(0.4203-7.439) 0.4369 1.297(0.2802-6.001) 0.7396 1
rs403636 C Allele 645 677 1   1   
A Allele 319 341 0.9808(0.8089-1.189) 0.8435 0.9492(0.7711-1.168) 0.6232 1
CC 208 220 1   1   
AC 229 237 1.0220(0.7860-1.3288) 0.87099199 1.0459(0.7870-1.3900) 0.756883 1
AA 45 52 0.9153(0.5884-1.4238) 0.6946183 0.7948(0.4921-1.2836) 0.347614 1
Dom    1.003(0.7798-1.29) 0.9826 0.9992(0.7614-1.311) 0.9952 1
Rec    0.905(0.5946-1.377) 0.6413 0.7838(0.4989-1.232) 0.2907 1
rs2937639 T Allele 816 878 1   1   
C Allele 150 142 1.136(0.8864-1.456) 0.3137 1.128(0.8626-1.476) 0.3783 1
TT 344 379 1   1   
CT 128 120 1.1752(0.8805-1.5684) 0.27303583 1.1803(0.8642-1.6120) 0.297244 1
CC 11 11 1.1017(0.4717-2.5736) 0.82287421 1.0280(0.4145-2.5496) 0.952512 1
Dom    1.169(0.8837-1.546) 0.2739 1.169(0.8636-1.582) 0.3123 1
Rec    1.057(0.4541-2.462) 0.8974 0.9771(0.3924-2.433) 0.9603 1
rs3756450 A Allele 506 535 1   1   
G Allele 454 485 0.989(0.8238-1.187) 0.9055 1.018(0.8355-1.24) 0.8615 1
AA 124 133 1   1   
AG 258 269 1.0287(0.7633-1.3864) 0.85244842 1.0910(0.7906-1.5055) 0.596073 1
GG 98 108 0.9733(0.6743-1.4047) 0.8849171 1.0310(0.6914-1.5373) 0.881023 1
Dom    1.013(0.7622-1.346) 0.9299 1.073(0.7889-1.458) 0.6547 1
Rec    0.9549(0.7023-1.298) 0.7685 0.9685(0.6952-1.349) 0.8497 1
rs2550946 A Allele 823 886 1   1   
G Allele 143 134 1.148(0.8909-1.479) 0.2859 1.141(0.8671-1.501) 0.3463 1
AA 350 386 1   1   
AG 123 114 1.1899(0.8877-1.5951) 0.24476629 1.2021(0.8760-1.6495) 0.254198 1
GG 10 10 1.1029(0.4536-2.6813) 0.82898896 1.0040(0.3872-2.6035) 0.99349 1
Dom    1.183(0.8902-1.572) 0.2468 1.186(0.8724-1.613) 0.2761 1
Rec    1.057(0.4361-2.563) 0.9022 0.9507(0.3652-2.475) 0.9176 1
rs12652860 C Allele 595 615 1   1   
A Allele 371 403 0.9467(0.7832-1.144) 0.5712 0.9343(0.761-1.147) 0.5166 1
CC 173 174 1   1   
AC 249 267 0.9380(0.7144-1.2314) 0.64476562 0.9233(0.6859-1.2428) 0.598692 1
AA 61 68 0.9022(0.6020-1.3523) 0.6183072 0.8904(0.5778-1.3720) 0.598766 1
Dom    0.9307(0.7169-1.208) 0.5898 0.9163(0.691-1.215) 0.544 1
Rec    0.9374(0.6472-1.358) 0.7326 0.9203(0.6162-1.374) 0.6849 1
rs12654851 G Allele 536 549 1   1   
T Allele 430 471 0.9285(0.771-1.118) 0.4343 0.9315(0.7625-1.138) 0.4869 1
GG 137 136 1   1   
GT 262 277 0.9389(0.7017-1.2564) 0.67158199 0.9964(0.7282-1.3633) 0.981816 1
TT 84 97 0.8597(0.5900-1.2525) 0.43094129 0.8456(0.5610-1.2747) 0.423275 1
Dom    0.9184(0.695-1.214) 0.5493 0.9584(0.7095-1.295) 0.782 1
  Rec    0.8964(0.649-1.238) 0.5066 0.8546(0.6038-1.21) 0.3754 1
  1. Bold data: adjusted p value < 0.05.