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Table 1 Changes of spatial learning and memory function of chronic aluminum overload rats (mean ± SD, n = 10)

From: Hippocampal neuronal metal ion imbalance related oxidative stress in a rat model of chronic aluminum exposure and neuroprotection of meloxicam

Group Latency (s)
Day 1 Day 2 Day 3 Day 4 Day 5
Control group 100.21 ± 9.38 75.32 ± 9.51 42.16 ± 7.24 20.31 ± 4.88 14.24 ± 3.38
M-3 group 96.28 ± 8.51 65.37 ± 7.32 33.46 ± 6.27 19.34 ± 4.08 12.04 ± 3.22
M-1 group 104.36 ± 12.14 72.52 ± 9.11 40.66 ± 7.16 23.11 ± 4.25 15.43 ± 4.39
Model group 158.42 ± 24.03** 102.56 ± 11.36** 70.53 ± 7.58** 53.16 ± 6.24** 45.14 ± 6.13**
Al + M-3 group 99.33 ± 9.18## 69.51 ± 8.17## 38.69 ± 5.11##a 20.14 ± 4.22##a 16.14 ± 4.10##a
Al + M-1 group 114.18 ± 8.68## 79.33 ± 9.41## 53.18 ± 7.59## 36.17 ± 4.56# 24.23 ± 3.62#
  1. **P < 0.01, vs. control group; #P < 0.05, ##P < 0.01, vs. model group; aP < 0.05, vs. Al + M-1 group; M-3 group: meloxicam 3 mg · kg−1 group; M-1 group: meloxicam 1 mg · kg−1 group; Al + M-3 group: Al + meloxicam 3 mg · kg−1 group; Al + M-1 group: Al + meloxicam 1 mg · kg−1 group.