Long-term effects of a single adult methamphetamine challenge: Minor impact on dopamine fibre density in limbic brain areas of gerbils

Table 1 Comparison of age-related long-term effects of a single methamphetamine intoxication on the dopamine innervation in limbocortical areas of the gerbil brain.

		Adult (current study) MA 1 × 25 mg/kg i.p., p180	Juvenile [Reference] MA 1 × 50 mg/kg i.p., p14
Prefrontal cortex	Medial	↔ n.s.	↓ – 38% ** [14]
	Orbital	↔ n.s.	↓ – 50% ** [14]
Nucleus accumbens	Core	↔ n.s.	↓ – 28% * [15]
	Shell	↑ +11% *	↔ n.s. [15]
Amygdala	Basolateral	↔ n.s.	↑ +18% ** [12]
	Central	↔ n.s.	↔ n.s. [12]
Olfactory Tubercle		↔ n.s	No data

ISSN: 1744-9081