From: Variation at APOE and STH loci and Alzheimer's disease
 | APOE alleles | Exact p-values | STH alleles | Exact p-values |  | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | ε 2 | ε 3 | ε 4 | Total | ε 2 | ε 3 | ε 4 | Total | Q | R | Total |  |  | |||||
 | f | n | f | n | f | n | 2N |  |  |  |  | f | n | f | n | 2N |  |  |
AD | 0.024 | 17 | 0.617 | 443 | 0.359 | 258 | 718 | 0.001 | 6.0*10-12 | 2.4*10-18 | 1.2*10-18 | 0.767 | 439 | 0.233 | 133 | 572 | 0.345 | 1 |
EOAD | 0.017 | 6 | 0.590 | 203 | 0.392 | 135 | 344 | 0.002 | 4.7*10-11 | 6.8*10-17 | 2.5*10-17 | 0.771 | 216 | 0.229 | 64 | 280 | 0.506 | 2 |
LOAD | 0.027 | 10 | 0.644 | 237 | 0.329 | 121 | 368 | 0.022 | 3.6*10-7 | 3.1*10-11 | 5.5*10-11 | 0.762 | 218 | 0.238 | 68 | 286 | 0.348 | 2 |
FH+ | 0.014 | 5 | 0.590 | 204 | 0.396 | 137 | 346 | 6.8*10-4 | 4.9*10-11 | 2.1*10-16 | 2.3*10-17 | 0.737 | 205 | 0.263 | 73 | 278 | 0.094 | 2 |
FH- | 0.030 | 11 | 0.641 | 232 | 0.329 | 119 | 362 | 0.051 | 2.2*10-7 | 4.1*10-11 | 1.1*10-10 | 0.796 | 226 | 0.204 | 58 | 284 | 1.000 | 2 |
Male | 0.032 | 9 | 0.635 | 179 | 0.333 | 94 | 282 | 0.093 | 3.9*10-5 | 1.7*10-7 | 3.9*10-7 | 0.738 | 155 | 0.262 | 55 | 210 | 0.145 | 3 |
Female | 0.018 | 8 | 0.606 | 264 | 0.376 | 164 | 436 | 0.008 | 7.0*10-8 | 9.8*10-12 | 4.9*10-12 | 0.785 | 284 | 0.215 | 78 | 362 | 1.000 | 3 |
Controls | 0.061 | 30 | 0.801 | 394 | 0.138 | 68 | 492 | Â | Â | Â | Â | 0.794 | 313 | 0.206 | 81 | 394 | Â | Â |
Male | 0.065 | 15 | 0.800 | 184 | 0.135 | 31 | 230 | Â | Â | Â | Â | 0.805 | 140 | 0.195 | 34 | 174 | Â | Â |
Female | 0.057 | 15 | 0.802 | 210 | 0.141 | 37 | 262 | Â | Â | Â | Â | 0.786 | 173 | 0.214 | 47 | 220 | Â | Â |