Refined mapping of Xp22.3 deletions. a. Positions of microsatellite and FISH markers used to map breakpoints are indicated below ideogram. Black bars denote nondeleted X chromosome segments; gray bars denote segments whose status is uncertain. Positions of RefSeq http://www.ncbi.nlm.nih.gov/RefSeq annotated genes ) are indicated above physical map scale. Marker and gene locations are from the UC Santa Cruz Genome Browser http://genome.ucsc.edu, March 2006 (hg18) assembly. b. High resolution mapping of deletions in subject 429 (son of 430) and subject 701 (son of 702) by array comparative genomic hybridization using an X chromosome tiling array. Each dot represents mean log2 signal intensity ratio of probes within consecutive 4000 bp intervals.