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Table 1 Mean (+ SD) novelty seeking and harm avoidance scores dependent on an individual's COMT and DRD2 genotype

From: An association study of DRD2 and COMT polymorphisms with novelty seeking and harm avoidance scores, in two independent samples of depressed patients

DRD2 COMT N Mean (± SD)
Clinical Sample 1    
Novelty seeking    
A1 absent Val absent 19 56.2 ± 14.0
  Val present 69 51.8 ± 18.3
A1 present Val absent 19 47.4 ± 13.6
  Val present 39 51.0 ± 15.1
DRD2 main effect    F (1,142) = 2.38, p = 0.125
COMT main effect    F (1,142) = 0.015, p = 0.901
DRD2 × COMT    F (1,142) = 1.62, p = 0.206
Harm avoidance    
A1 absent Val absent 19 70.8 ± 15.9
  Val present 69 67.0 ± 21.0
A1 present Val absent 19 66.9 ± 23.4
  Val present 39 66.3 ± 19.8
DRD2 main effect    F (1,142) = 0.356, p = 0.552
COMT main effect    F (1,142) = 0.319, p = 0.573
DRD2 × COMT    F (1,142) = 0.165, p = 0.685
Clinical Sample 2    
Novelty seeking    
A1 absent Val absent 16 48.3 ± 18.5
  Val present 62 47.9 ± 15.9
A1 present Val absent 14 46.4 ± 12.5
  Val present 54 47.9 ± 14.0
DRD2 main effect    F (1,142) = 0.087, p = 0.769
COMT main effect    F (1,142) = 0.027, p = 0.870
DRD2 × COMT    F (1,142) = 0.088, p = 0.767
Harm avoidance    
A1 absent Val absent 16 70.7 ± 18.1
  Val present 62 72.3 ± 15.9
A1 present Val absent 14 73.1 ± 17.5
  Val present 54 69.3 ± 22.1
DRD2 main effect    F (1,142) = 0.008, p = 0.928
COMT main effect    F (1,142) = 0.082, p = 0.775
DRD2 × COMT    F (1,142) = 0.489, p = 0.485