Table 1 Genotypic, Allelic and Haplotype association study of PPP3CC -CC33 and -CCS3 polymorphisms

CC33

CC

39

46

(CT+TT) versus CC 1.8 [1.01–3.0]

0.05

CT

52

36

TT

24

15

f(C)

0.57

0.66

-

f(T)

0.43

0.34

1.5 [1.01–2.2]

0.05

CCS3

Allele frequencies

Cases

Controls

OR [CI_95%]

p-value

AA

22

39

(GG+AG) vs AA 2.8 [1.5–5.2]

0.001

AG

60

41

GG

27

14

f(A)

0.48

0.63

-

f(G)

0.52

0.37

1.9 [1.3–2.8]

0.002

CC33/CCS3

Haplotype frequencies

Cases

Controls

Chi-Square

p-value

CA

0.47

0.61

TG versus (C2+CG+TA) 16.2

0.001

CG

0.09

0.05

TA

-

0.02

TG

0.44

0.32