Table 2 The Number and Severity of Adverse Events Experienced by the Subjects during the Study (only those events with ≥ 5% frequency are shown).
From: A randomized controlled trial of a novel mixed monoamine reuptake inhibitor in adults with ADHD
NS2359 | Placebo | ||||||
|---|---|---|---|---|---|---|---|
Body System | Symptom | Mild | Mod | Severe | Mild | Mod | Severe |
Gastrointestinal Disorders | Diarrhea NOS | 4 | 1 | 0 | 0 | 0 | 0 |
Dry Mouth | 5 | 3 | 0 | 7 | 0 | 0 | |
Dyspepsia | 6 | 0 | 0 | 3 | 1 | 0 | |
Nausea | 4 | 1 | 0 | 6 | 0 | 1 | |
General disorders and administration site conditions | Fatigue | 1 | 2 | 0 | 7 | 0 | 0 |
Infections & Infestations | Nasopharyngitis | 3 | 1 | 0 | 4 | 0 | 1 |
Upper Respiratory Tract infection | 6 | 1 | 0 | 5 | 2 | 0 | |
Investigations | Weight decrease | 5 | 1 | 0 | 0 | 0 | 0 |
Metabolism and nutrition disorders | Appetite decreased NOS | 5 | 1 | 0 | 6 | 0 | 0 |
Musculoskeletal and Connective Tissue Disorders | Back Pain | 1 | 1 | 0 | 5 | 1 | 0 |
Nervous system Disorders | Dizziness | 5 | 2 | 0 | 3 | 0 | 0 |
Headache NOS | 15 | 6 | 1 | 15 | 5 | 1 | |
Irregular Sleep Phases | 3 | 0 | 1 | 2 | 0 | 0 | |
Somnolence | 0 | 0 | 0 | 4 | 1 | 0 | |
Psychiatric disorders | Initial Insomnia | 1 | 3 | 0 | 2 | 0 | 0 |
Insomnia | 8 | 3 | 1 | 2 | 0 | 1 | |
Irritability | 5 | 1 | 0 | 0 | 2 | 0 | |
Middle Insomnia | 7 | 0 | 0 | 1 | 0 | 0 | |