Table 1 Genotype and allele distribution of six SNPs of the FZD3 gene in controls and patients with methamphetamine (MAP) psychosis
From: The Frizzled 3 gene is associated with methamphetamine psychosis in the Japanese population
| Â | Â | Genotype | p | Allele | p | ||||
|---|---|---|---|---|---|---|---|---|---|
SNP1 | rs3757888 | N | A/A | A/G | G/G | Â | A | G | Â |
Control | Â | 230 | 198(86.1) | 31(13.5) | 1(0.4) | Â | 427(92.8) | 33(7.2) | Â |
MAP Psychosis | Â | 186 | 151(81.2) | 32(7.2) | 3(1.61) | 0.26 | 334(89.8) | 38(10.2) | 0.19 |
SNP2 | rs960914 | N | T/T | T/C | C/C | Â | T | C | Â |
Control | Â | 240 | 67(27.9) | 130(54.2) | 43(17.9) | Â | 264(55.0) | 216(45.0) | Â |
MAP Psychosis | Â | 185 | 45(24.3) | 103(55.7) | 37(20.0) | 0.66 | 193(52.2) | 177(47.8) | 0.41 |
SNP3 | rs2241802 | N | A/A | A/G | G/G | Â | A | G | Â |
Control | Â | 240 | 49(20.4) | 124(51.7) | 67(27.9) | Â | 222(46.2) | 258(53.8) | Â |
MAP Psychosis | Â | 181 | 44(24.3) | 97(53.6) | 40(22.1) | 0.34 | 185(51.1) | 177(48.9) | 0.16 |
SNP4 | rs2323019 | N | A/A | A/G | G/G | Â | A | G | Â |
Control | Â | 239 | 72(31.4) | 113(49.3) | 44(19.2) | Â | 257(56.1) | 201(43.9) | Â |
MAP Psychosis | Â | 186 | 45(24.1) | 101(54.0) | 41(21.9) | 0.25 | 191((51.1) | 183(48.9) | 0.15 |
SNP5 | rs352203 | N | T/T | T/C | C/C | Â | T | C | Â |
Control | Â | 192 | 64(33.3) | 98(51.1) | 30(15.6) | Â | 226(58.9) | 158(41.1) | Â |
MAP Psychosis | Â | 176 | 49(27.8) | 98(55.7) | 29(16.5) | 0.52 | 196(55.7) | 156(44.3) | 0.38 |
SNP6 | rs880481 | N | A/A | A/G | G/G | Â | A | G | Â |
Control | Â | 236 | 43(18.2) | 123(52.1) | 70(29.7) | Â | 209(44.3) | 263(55.7) | Â |
MAP Psychosis | Â | 186 | 30(16.1) | 103(55.4) | 53(28.5) | 0.97 | 163(43.8) | 209(56.2) | 0.99 |