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Table 2 Structure and sizes of pedigrees (Sample 4)

From: Recessive genetic mode of an ADH4 variant in substance dependence in African-Americans: A model of utility of the HWD test

 

Total

EAs

AAs

Others

Subjects

1613

766

833

14

   %Male

46.3

51.4

41.2

71.4

   Age (year)

39.4 ± 8.9

37.8 ± 10.2

40.8 ± 7.2

43.7 ± 5.7

Pedigrees

632

311

316

5

   With 1 AD

242

115

126

1

   With 2 AD

166

87

78

1

   With 3 AD

11

5

6

0

   With 4 AD

5

2

3

0

   With ≥ 5 AD

1

0

1

0

   With 1 DD

57

25

32

0

   With 2 DD

460

243

216

1

   With 3 DD

90

35

55

0

   With 4 DD

16

7

9

0

   With ≥ 5 DD

3

0

3

0

  1. EA, AA, AD, DD, same as Table 1. "With n AD", a pedigree having n offspring with AD; as analogy.