Skip to main content

Advertisement

Table 3 Changes in median expression and corresponding null probability values () for pair-wise comparison of disease classes and the non-fatigued control group under both classification systems

From: Evidence of inflammatory immune signaling in chronic fatigue syndrome: A pilot study of gene expression in peripheral blood

    3-Class (NF Controls) 7-Class (Controls = LCA-0 U LCA-2)
Cell Type Expression Level +/- Number of genes ISF CFS LCA-1 LCA-3 LCA-4 LCA-5 LCA-6
CD8 T cells Up-regulated 5 0.06 (0.43) 0.01 (0.75) 0.06 (0.52) 0.00 (0.64) 0.04 (0.24) 0.01 (0.80) 0.23 (0.27)
  Down-regulated         
CD14 Monocytes Up-regulated 78 0.04 (0.29) 0.05 (0.83) 0.02 (0.62) 0.11 (0.15) 0.09 (0.42) 0.02 (0.94) 0.05 (0.33)
  Down-regulated         
CD16 Neutrophils Up-regulated         
  Down-regulated 185 0.02 (0.20) 0.02 (0.25) 0.02 (0.29) 0.00 (0.65) 0.03 (0.25) 0.02 (0.50) 0.04 (0.30)
CD19 B cells Up-regulated 6 -0.17 (0.05) -0.28 (0.01) -0.27 (0.29) -0.31 (0.04) -0.12 (0.13) -0.25 (0.09) -0.17 (0.14)
  Down-regulated 2 -0.22 (0.33) -0.22 (0.29) -0.18 (0.19) 0.07 (0.71) 0.10 (0.76) -0.08 (0.78) -0.08 (0.16)
CD4/8/25 T reg cells NA 1 -0.23 (0.19) -0.23 (0.31) -0.35 (0.09) 0.19 (0.37) -0.25 (0.11) -0.17 (0.32) 0.28 (0.40)
NK cells NA 4 0.09 (0.92) 0.30 (0.07) 0.19 (0.20) 0.32 (0.11) 0.12 (0.68) 0.12 (0.45) -0.01 (0.57)