Table 3 Changes in median expression and corresponding null probability values () for pair-wise comparison of disease classes and the non-fatigued control group under both classification systems
| Â | Â | Â | 3-Class (NF Controls) | 7-Class (Controls = LCA-0 U LCA-2) | |||||
|---|---|---|---|---|---|---|---|---|---|
Cell Type | Expression Level +/- | Number of genes | ISF | CFS | LCA-1 | LCA-3 | LCA-4 | LCA-5 | LCA-6 |
CD8 T cells | Up-regulated | 5 | 0.06 (0.43) | 0.01 (0.75) | 0.06 (0.52) | 0.00 (0.64) | 0.04 (0.24) | 0.01 (0.80) | 0.23 (0.27) |
| Â | Down-regulated | Â | Â | Â | Â | Â | Â | Â | Â |
CD14 Monocytes | Up-regulated | 78 | 0.04 (0.29) | 0.05 (0.83) | 0.02 (0.62) | 0.11 (0.15) | 0.09 (0.42) | 0.02 (0.94) | 0.05 (0.33) |
| Â | Down-regulated | Â | Â | Â | Â | Â | Â | Â | Â |
CD16 Neutrophils | Up-regulated | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | Down-regulated | 185 | 0.02 (0.20) | 0.02 (0.25) | 0.02 (0.29) | 0.00 (0.65) | 0.03 (0.25) | 0.02 (0.50) | 0.04 (0.30) |
CD19 B cells | Up-regulated | 6 | -0.17 (0.05) | -0.28 (0.01) | -0.27 (0.29) | -0.31 (0.04) | -0.12 (0.13) | -0.25 (0.09) | -0.17 (0.14) |
| Â | Down-regulated | 2 | -0.22 (0.33) | -0.22 (0.29) | -0.18 (0.19) | 0.07 (0.71) | 0.10 (0.76) | -0.08 (0.78) | -0.08 (0.16) |
CD4/8/25 T reg cells | NA | 1 | -0.23 (0.19) | -0.23 (0.31) | -0.35 (0.09) | 0.19 (0.37) | -0.25 (0.11) | -0.17 (0.32) | 0.28 (0.40) |
NK cells | NA | 4 | 0.09 (0.92) | 0.30 (0.07) | 0.19 (0.20) | 0.32 (0.11) | 0.12 (0.68) | 0.12 (0.45) | -0.01 (0.57) |