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Figure 1 | Behavioral and Brain Functions

Figure 1

From: Time estimation in mild Alzheimer's disease patients

Figure 1

SET information-processing model applied to time bisection tasks. In the SET model, a pacemaker emits pulses that are gated by a switch during the current to-be-timed interval (T) and sent to an accumulator. The corresponding number of pulses are stored in working memory and compared with that of reference short (S) and long (L) intervals previously stored in reference memory during the training phase. According to a similarity rule based on the S/T and T/L ratios, T will be estimated to be more similar to either of the two reference values and a response (either "SHORT" or "LONG") will be produced. According to STT model, the clock stage is controlled by the dopaminergic system, whereas the memory stage is dependent on the cholinergic system.

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