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Table 1 Effect of LDX on Sleep Onset (in minutes) as Assessed by the PSQI

From: Effect of lisdexamfetamine dimesylate on sleep in adults with attention-deficit/hyperactivity disorder

 

Placebo

(n = 62)

30 mg/d LDX

(n = 119)

50 mg/d LDX

(n = 116)

70 mg/d LDX

(n = 121)

All LDX Doses

(n = 356)

Baseline

[Mean (SD)]

30.2

(28.34)

22.6

(20.84)

26.6

(26.44)

25.1

(24.56)

24.8

(24.03)

Endpoint

[Mean (SD)]

28.1

(32.64)

20.1

(18.23)

27.9

(26.73)

29.3

(31.19)

25.9

(26.27)

Change

[LS Mean (SE)]

-1.2

(2.78)

-3.5

(2.09)

0.4

(2.06)

4.0

(2.04)

0.4

(1.23)

  1. Sleep onset reported in minutes.
  2. SD = standard deviation; SE = standard error; LS = least squares; PSQI = Pittsburgh Sleep Quality Index; LDX = lisdexamfetamine dimesylate.
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Behavioral and Brain Functions

ISSN: 1744-9081

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