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Table 1 Effect of LDX on Sleep Onset (in minutes) as Assessed by the PSQI

From: Effect of lisdexamfetamine dimesylate on sleep in adults with attention-deficit/hyperactivity disorder

  Placebo (n = 62) 30 mg/d LDX (n = 119) 50 mg/d LDX (n = 116) 70 mg/d LDX (n = 121) All LDX Doses (n = 356)
Baseline [Mean (SD)] 30.2 (28.34) 22.6 (20.84) 26.6 (26.44) 25.1 (24.56) 24.8 (24.03)
Endpoint [Mean (SD)] 28.1 (32.64) 20.1 (18.23) 27.9 (26.73) 29.3 (31.19) 25.9 (26.27)
Change [LS Mean (SE)] -1.2 (2.78) -3.5 (2.09) 0.4 (2.06) 4.0 (2.04) 0.4 (1.23)
  1. Sleep onset reported in minutes.
  2. SD = standard deviation; SE = standard error; LS = least squares; PSQI = Pittsburgh Sleep Quality Index; LDX = lisdexamfetamine dimesylate.