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Table 4 Comparison reductions in ARS scores after MPH treatment in ADHD subjects according to genotypes of the -3081(A/T) polymorphism

From: Possible association of norepinephrine transporter -3081(A/T) polymorphism with methylphenidate response in attention deficit hyperactivity disorder

Genotype

Changes in ARS scores

 

IA

p-value

Hy/Imp

p-value

Total

p-value

A/A

5.4 (4.3)

0.54

4.6 (4.1)

0.12

8.4 (7.6)

0.10

A/T

6.2 (4.9)

 

6.3 (4.5)

 

12.1 (8.8)

 

T/T

7.2 (6.6)

 

7.8 (7.2)

 

14.7 (12.6)

 

A/A

5.4 (4.3)

0.38

4.6 (4.1)

0.09

8.4 (7.6)

0.06

A/T + T/T

6.5 (5.4)

 

6.7 (5.4)

 

12.8 (10.0)

 
  1. ARS, ADHD Rating Scale; IA, inattentive subscale; Hy/Imp, hyperactivity/impulsivity subscale
  2. All values are mean (± S.D.)