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Figure 2 | Behavioral and Brain Functions

Figure 2

From: Effects of early life trauma are dependent on genetic predisposition: a rat study

Figure 2

Forced swim test behaviour of SHR and WKY males (M) and females (F), maternally separated (MS) or non-maternally separated (nMS). Time spent immobile (a and b), climbing (c and d) or swimming (e and f) is expressed as a percentage of total time. For each parameter, data are shown for the total 5-minute period (a, c, and e) and for each individual minute (b, d and f). a. *WKY spent more of the total 5-minute period immobile than SHR (p < 0.01). Maternal separation did not increase time spent immobile in either strain. b. *WKY spent more time immobile than SHR (p < 0.01). #SHR males spent more time immobile than SHR females in the 1st minute (p < 0.001). c. *SHR spent more of the total 5-minute period climbing than WKY (p < 0.05). d. *SHR spent more time climbing than WKY in the 1st minute (p < 0.001). @Maternal separation increased climbing in SHR in the 4th minute (p < 0.01). e. *SHR spent more of the total 5-minute period swimming than WKY (p < 0.05). f. *SHR spent more time swimming than WKY (p < 0.05). #Females spent more time swimming during the 1st minute than males (p < 0.01). (SHR males: nMS, n = 9, MS, n = 9; SHR females: nMS, n = 5, MS, n = 14; WKY males: nMS, n = 9; MS, n = 9; WKY females, nMS, n = 10, MS, n = 8).

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