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Table 3 Association analysis of the 5 SNPs in females

From: Possible association between Interleukin-1beta gene and schizophrenia in a Japanese population

    Males
SNP name Allele 1/2   N Genotype Allele P-value HWE P-value
     1/1 1/2 2/2 1 2 Genotype Allele  
rs2853550 A/G Schizophrenia 231 5 54 172 64 398 0.18 0.096 0.78
     (0.02) (0.23) (0.74) (0.14) (0.86)    
   Controls 732   7 147 578   161 1303 0.57
     (0.01) (0.20) (0.79) (0.11) (0.89)    
rs1143634 A/G Schizophrenia 227 1 17 209 19 435 0.46(a) 0.84 0.32
     (0.00) (0.07) (0.92) (0.04) (0.96)    
   Controls 738 1 63 674 65 1411    1.00
    (0.00) (0.09) (0.91) (0.04) (0.96)     
rs1143633 C/T Schizophrenia 225 52 104 69 208 242 0.013 0.0073 0.29
    (0.23) (0.46) (0.31) (0.46) (0.54)     
   Controls 740 111 357 272 579 901    0.76
    (0.15) (0.48) (0.37) (0.39) (0.61)     
rs1143630 T/G Schizophrenia 225 6 59 160 71 379 0.97 0.83 0.80
    (0.03) (0.26) (0.71) (0.16) (0.84)     
   Controls 736 18 190 528 226 1246    0.89
    (0.02) (0.26) (0.72) (0.15) (0.85)     
rs16944 A/G Schizophrenia 226 57 110 59 224 228 0.11 0.032 0.69
    (0.25) (0.49) (0.26) (0.50) (0.50)     
   Controls 726 144 348 234 636 816    0.50
    (0.20) (0.48) (0.32) (0.44) (0.56)     
  1. (a) Calculated using Fisher's exact test.
  2. SNP: single nucleotide polymorphism; HWE: Hardy-Weinberg Disequilibrium
  3. Numbers in parentheses represent the frequencies of genotypes and alleles. Significant P-values (< 0.013) are shown in boldface.