From: Update in the methodology of the chronic stress paradigm: internal control matters
Category | Function | Anhedonic | Resilient | ||||
---|---|---|---|---|---|---|---|
 |  | # Genes Up | # Genes Down | p-value | # Genes Up | # Genes Down | p-value |
Cellular Assembly and Organization | transport of vesicles | Â | Â | N.S. | 41 | Â | 4.22E-07 |
 | biogenesis of cytoskeleton |  |  | N.S. | 35 | 3 | 5.41E-06 |
 | morphogenesis of neurites |  |  | N.S. | 33 |  | 7.25E-06 |
 | formation of vesicles |  |  | N.S. | 25 |  | 2.04E-05 |
 | formation of filaments | 11 | 13 | 4.47E-05 |  |  | N.S. |
 | formation of neurites | 4 | 8 | 8.47E-05 |  |  | N.S. |
Behavior | cognition | 9 | 6 | 2.62E-03 | 57 | 1 | 2.97E-06 |
 | behavior | 30 | 16 | 1.29E-04 |  |  | N.S. |
 | learning |  |  | N.S. | 48 | 1 | 2.13E-05 |
 | psychological process of mice | 23 | 10 | 2.49E-04 |  |  | N.S. |
 | memory | 10 | 5 | 3.01E-04 |  |  | N.S. |
 | exploratory behavior of mice | 6 | 1 | 1.80E-04 | 14 |  | 5.37E-04 |
Cellular Movement | movement of brain cells | Â | Â | N.S. | 30 | 1 | 3.40E-06 |
 | migration of brain cells |  |  | N.S. | 29 | 1 | 4.59E-06 |
Nervous System Development and Function | development of neurites | 18 | 4 | 1.67E-05 | 63 | Â | 6.50E-06 |
 | development of axons | 11 | 4 | 3.10E-05 | 34 |  | 1.35E-03 |
 | long-term potentiation | 10 | 5 | 2.54E-03 | 50 | 3 | 1.60E-05 |
 | long term depression | 6 | 3 | 5.95E-04 |  |  | N.S. |
 | synaptic transmission | 13 | 6 | 2.77E-05 | 50 |  | 1.29E-04 |
 | prepulse inhibition of mice | 8 | 2 | 2.66E-06 |  |  | N.S. |
 | coordination of mice | 5 | 2 | 9.73E-05 |  |  | N.S. |
 | memory | 10 | 5 | 3.01E-04 |  |  | N.S. |
 | spatial memory of mice | 5 | 3 | 3.96E-04 |  |  | N.S. |
 | neurological process | 25 | 19 | 4.65E-08 | 107 | 4 | 1.30E-03 |
 | neurotransmission | 17 | 7 | 6.95E-07 | 57 |  | 1.30E-04 |
Neurological Disease | seizures | Â | Â | N.S. | 35 | 1 | 1.11E-04 |
 | dyskinesia |  |  | N.S. | 76 | 2 | 1.86E-04 |
 | Huntington's disease | 18 | 11 | 2.11E-06 | 75 | 1 | 2.06E-04 |
 | neurological disorder | 42 | 41 | 2.36E-06 | 258 | 11 | 5.50E-03 |
 | neurodegeneration of neurons | 8 | 3 | 2.75E-04 | 27 |  | 6.10E-04 |