SNP | Genotype | N | Before treatment | After 8 weeks treatment | Reduction rate (%)* | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  | Total** | P a | N b | G c | total | P a | N b | G c |  |
rs27647 | GG | 292 | 88.06 ± 21.64 | 24.49 ± 6.63 | 21.46 ± 8.00 | 42.11 ± 12.34 | 45.84 ± 12.63 | 10.87 ± 3.69 | 11.65 ± 4.85 | 23.32 ± 6.33 | 0.72 ± 0.19 |
 | GA+AA | 88 | 87.38 ± 23.51 | 23.05 ± 6.92 | 22.81 ± 8.28 | 41.52 ± 13.4 | 45.40 ± 10.86 | 10.68 ± 3.53 | 12.24 ± 5.05 | 22.48 ± 4.88 | 0.72 ± 0.19 |
 | P |  | 0.799 | 0.076 | 0.169 | 0.702 | 0.767 | 0.672 | 0.321 | 0.250 | 0.988 |
rs26802 | AA | 322 | 88.61 ± 22.47 | 24.35 ± 6.80 | 21.74 ± 8.26 | 42.52 ± 12.76 | 45.91 ± 12.47 | 10.90 ± 3.76 | 11.76 ± 4.97 | 23.25 ± 6.17 | 0.72 ± 0.19 |
 | AC+CC | 58 | 83.97 ± 19.33 | 23.09 ± 6.16 | 21.91 ± 7.00 | 38.97 ± 11.20 | 44.79 ± 10.85 | 10.43 ± 2.96 | 11.93 ± 4.49 | 22.43 ± 5.15 | 0.72 ± 0.18 |
 | P |  | 0.140 | 0.187 | 0.882 | 0.048 | 0.524 | 0.371 | 0.805 | 0.341 | 0.929 |
rs696217 | GG | 253 | 87.91 ± 22.94 | 24.23 ± 6.53 | 21.66 ± 8.36 | 42.02 ± 13.15 | 45.09 ± 11.31 | 10.63 ± 3.60 | 11.61 ± 4.70 | 22.85 ± 5.34 | 0.73 ± 0.18 |
 | GT+TT | 120 | 87.65 ± 19.38 | 24.11 ± 6.96 | 21.82 ± 7.36 | 41.73 ± 10.91 | 45.97 ± 11.41 | 11.01 ± 3.31 | 11.74 ± 4.70 | 23.22 ± 6.10 | 0.71 ± 0.20 |
 | P |  | 0.915 | 0.870 | 0.864 | 0.834 | 0.484 | 0.329 | 0.798 | 0.555 | 0.309 |
rs26311 | CC | 153 | 87.25 ± 22.59 | 24.09 ± 6.84 | 21.58 ± 7.52 | 41.58 ± 13.06 | 45.30 ± 11.10 | 10.85 ± 3.70 | 11.52 ± 4.52 | 22.93 ± 5.35 | 0.72 ± 0.19 |
 | GG+GC | 223 | 87.66 ± 21.04 | 24.09 ± 6.59 | 21.74 ± 8.36 | 41.83 ± 11.82 | 46.01 ± 13.04 | 10.79 ± 3.63 | 11.96 ± 5.15 | 23.25 ± 6.49 | 0.72 ± 0.19 |
 | P |  | 0.857 | 0.998 | 0.845 | 0.848 | 0.582 | 0.884 | 0.385 | 0.619 | 0.883 |