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Table 6 Reduction of PANSS scores in patients with different GHRL genotypes ( x - ± s )

From: Association between Ghrelin gene (GHRL) polymorphisms and clinical response to atypical antipsychotic drugs in Han Chinese schizophrenia patients

SNP Genotype N Before treatment After 8 weeks treatment Reduction rate (%)*
    Total** P a N b G c total P a N b G c  
rs27647 GG 292 88.06 ± 21.64 24.49 ± 6.63 21.46 ± 8.00 42.11 ± 12.34 45.84 ± 12.63 10.87 ± 3.69 11.65 ± 4.85 23.32 ± 6.33 0.72 ± 0.19
  GA+AA 88 87.38 ± 23.51 23.05 ± 6.92 22.81 ± 8.28 41.52 ± 13.4 45.40 ± 10.86 10.68 ± 3.53 12.24 ± 5.05 22.48 ± 4.88 0.72 ± 0.19
  P   0.799 0.076 0.169 0.702 0.767 0.672 0.321 0.250 0.988
rs26802 AA 322 88.61 ± 22.47 24.35 ± 6.80 21.74 ± 8.26 42.52 ± 12.76 45.91 ± 12.47 10.90 ± 3.76 11.76 ± 4.97 23.25 ± 6.17 0.72 ± 0.19
  AC+CC 58 83.97 ± 19.33 23.09 ± 6.16 21.91 ± 7.00 38.97 ± 11.20 44.79 ± 10.85 10.43 ± 2.96 11.93 ± 4.49 22.43 ± 5.15 0.72 ± 0.18
  P   0.140 0.187 0.882 0.048 0.524 0.371 0.805 0.341 0.929
rs696217 GG 253 87.91 ± 22.94 24.23 ± 6.53 21.66 ± 8.36 42.02 ± 13.15 45.09 ± 11.31 10.63 ± 3.60 11.61 ± 4.70 22.85 ± 5.34 0.73 ± 0.18
  GT+TT 120 87.65 ± 19.38 24.11 ± 6.96 21.82 ± 7.36 41.73 ± 10.91 45.97 ± 11.41 11.01 ± 3.31 11.74 ± 4.70 23.22 ± 6.10 0.71 ± 0.20
  P   0.915 0.870 0.864 0.834 0.484 0.329 0.798 0.555 0.309
rs26311 CC 153 87.25 ± 22.59 24.09 ± 6.84 21.58 ± 7.52 41.58 ± 13.06 45.30 ± 11.10 10.85 ± 3.70 11.52 ± 4.52 22.93 ± 5.35 0.72 ± 0.19
  GG+GC 223 87.66 ± 21.04 24.09 ± 6.59 21.74 ± 8.36 41.83 ± 11.82 46.01 ± 13.04 10.79 ± 3.63 11.96 ± 5.15 23.25 ± 6.49 0.72 ± 0.19
  P   0.857 0.998 0.845 0.848 0.582 0.884 0.385 0.619 0.883
  1. *reduction rates of PANSS total scores; ** total scores; a Positive score; b negative score; c general pathology score