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Table 1 Results of the association analyses

From: Association of CTXN3-SLC12A2 polymorphisms and schizophrenia in a Thai population

dbSNP ID

Type of SNP

 

Genotype frequencies

MAF1

P 2

Allelic OR3 Generalized OR

rs7711139

CTXN3

 

A/A

A/G

G/G

 

a

0.139

1.29(0.96–1.74)

 

intronic

Patients

17

45

52

0.34

d

0.528

1.23(0.84–1.95)

  

Controls

13

74

85

0.29

r

0.047

 

rs248707

CTXN3

 

C/C

C/T

T/T

 

a

0.594

1.24(0.88–1.74)

 

3′UTR

Patients

7

40

67

0.24

d

0.325

1.27(0.80–2.00)

  

Controls

8

53

111

0.20

r

0.580

 

rs1421746

Intergenic

 

C/C

C/T

T/T

 

a

0.025

0.61(0.46–0.81)

  

Patients

37

49

26

0.45

d

0.038

0.58(0.39–0.86)

  

Controls

38

71

64

0.57

r

0.015

 

rs698172

Intergenic

 

C/C

C/T

T/T

 

a

0.012

0.61(0.46–0.82)

  

Patients

49

41

21

0.38

d

0.003*

0.58(0.38–0.87)

  

Controls

47

81

45

0.49

r

0.167

 

rs698171

Intergenic

 

G/G

G/T

T/T

 

a

0.028

1.56(1.13–2.16)

  

Patients

57

44

11

0.29

d

0.10

1.58(1.01–2.48)

  

Controls

105

63

5

0.21

r

0.01

 

rs245201

Intergenic

 

A/A

A/G

G/G

 

a

0.083

0.81(0.60–1.08)

  

Patients

51

41

22

0.37

d

0.052

0.77(0.51–1.15)

  

Controls

56

82

30

0.42

r

0.759

 

rs245178

Intergenic

 

A/A

A/G

G/G

 

a

0.021

0.62(0.46–0.83)

  

Patients

54

43

15

0.33

d

0.006*

0.57(0.38–0.86)

  

Controls

55

83

34

0.44

r

0.165

 
  1. 1MAF: Minor allele frequency.
  2. 2P values for the additive model (a), dominant model (d), and recessive model (r) are shown. Asterisks indicate tests that were significant at 5% level after the Bonferroni correction for multiple SNP testing.
  3. 3Allelic OR (upper) indicates odds ratio and 95% confidence interval of minor alleles. Generalized OR (lower) indicates odds ratio and 95% confidence interval of genotypes [14].